Genetics of presbycusis and presbystasis

被引：26

作者：

Ciorba, A. ^{[1
]}

Hatzopoulos, S. ^{[1
]}

Bianchini, C. ^{[1
]}

Aimoni, C. ^{[1
]}

Skarzynski, H. ^{[2
,3
]}

Skarzynski, P. H. ^{[2
,4
]}

机构：

[1] Univ Ferrara, ENT & Audiol Dept, I-44100 Ferrara, Italy

[2] Inst Physiol & Pathol Hearing, Warsaw, Poland

[3] World Hearing Ctr, Kajetany, Poland

[4] Med Univ Warsaw, Dept Heart Failure & Cardiac Rehabil, Warsaw, Poland

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2015年 / 28卷 / 01期

关键词：

age-related hearing loss; animal models; genetic; presbycusis; presbystasis; RECURRENT VERTIGO; RISK-FACTORS; HEARING-LOSS; IMPAIRMENT; LINKAGE; LOCUS;

D O I：

10.1177/0394632015570819

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Presbycusis and presbystasis represent relevant problems of aging, caused by the increase in life expectancy in developed countries. As such, it is advantageous to better understand the physiopathological mechanisms of these age-related inner ear diseases. The hypothesis that presbycusis and presbystasis have a genetic background was proposed some years ago. Several studies (in humans and animals) are available in the literature, and possible genes involved in the physiopathology of both diseases have been identified. The aim of this paper is to present an overview of the information available in the current medical literature on presbycusis and presbystasis.

引用

页码：29 / 35

页数：7

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