Synthesis of thiohydantoins under one-pot three-component solvent-free conditions

被引：11
|
作者：
Cao, Song [1 ,2 ]
Zhu, Longjie [1 ]
Zhao, Chuanmeng [1 ]
Tang, Xiuhong [1 ]
Sun, Huajun [1 ]
Feng, Xin [1 ]
Qian, Xuhong [1 ]
机构：
[1] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
MONATSHEFTE FUR CHEMIE | 2008年 / 139卷 / 08期
关键词：
heterocycles; multicomponent reactions; solvent-free; cyclizations; isothiocyanates;
D O I：
10.1007/s00706-007-0842-8
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A direct and efficient one-pot three-component synthesis protocol was developed for the synthesis of thiohydantoins from readily and widely available substrates (isothiocyanates, ethyl chloroacetate, and amines) employing solvent-free conditions.
引用
收藏
页码：923 / 926
页数：4
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