Synthesis of Functionalized Polycyclic Compounds: Rhodium(I)-Catalyzed Intramolecular Cycloaddition of Yne and Ene Vinylidenecyclopropanes

被引：34

作者：

Lu, Bei-Li ^{[1
]}

Shi, Min ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 50期

基金：

中国国家自然科学基金;

关键词：

cycloadditions; C?H bond activation; heterocycles; rhodium; synthetic methods; C-H ACTIVATION; SUBSTITUTED RHODIUM CARBENOIDS; ACID CATALYZED REACTION; BOND ACTIVATION; LEWIS-ACID; ORGANIC-SYNTHESIS; VINYLIDENE-CYCLOPROPANES; DERIVATIVES; REARRANGEMENT; CYCLIZATION;

D O I：

10.1002/anie.201105292

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three ring circus: The title reaction can efficiently provide functionalized polycyclic compounds containing cyclobutene (see scheme; PG=protecting group) or aza-cyclooctene moieties in a highly regio- and diastereoselective manner with moderate to good yields under mild reaction conditions. The scope and limitations are disclosed and plausible reaction mechanisms are discussed. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：12027 / 12031

页数：5

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