Porcine Deltacoronaviruses: Origin, Evolution, Cross-Species Transmission and Zoonotic Potential

被引:31
作者
Kong, Fanzhi [1 ]
Wang, Qiuhong [2 ,3 ]
Kenney, Scott P. [2 ,3 ]
Jung, Kwonil [2 ,3 ]
Vlasova, Anastasia N. [2 ,3 ]
Saif, Linda J. [2 ,3 ]
机构
[1] Heilongjiang Bayi Agr Univ, Coll Anim Sci & Vet Med, 5 Xinfeng Rd, Daqing 163319, Peoples R China
[2] Ohio State Univ, Dept Anim Sci, Coll Food Agr & Environm Sci, Ctr Food Anim Hlth, Wooster, OH 44691 USA
[3] Ohio State Univ, Coll Vet Med, Dept Vet Prevent Med, Columbus, OH 43210 USA
来源
PATHOGENS | 2022年 / 11卷 / 01期
关键词
porcine deltacoronaviruses; origin; evolution; cross-species transmission; zoonosis; INTESTINAL EPITHELIAL-CELLS; LENGTH GENOME SEQUENCE; GENETIC-CHARACTERIZATION; AVIAN CORONAVIRUSES; PIGS; PATHOGENICITY; STRAIN; EPIDEMIOLOGY; INFECTION; THAILAND;
D O I
10.3390/pathogens11010079
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus of swine that causes acute diarrhoea, vomiting, dehydration and mortality in seronegative neonatal piglets. PDCoV was first reported in Hong Kong in 2012 and its etiological features were first characterized in the United States in 2014. Currently, PDCoV is a concern due to its broad host range, including humans. Chickens, turkey poults, and gnotobiotic calves can be experimentally infected by PDCoV. Therefore, as discussed in this review, a comprehensive understanding of the origin, evolution, cross-species transmission and zoonotic potential of epidemic PDCoV strains is urgently needed.
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页数:17
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