Are we ready for industrial production of bioactive plant secondary metabolites utilizing endophytes?

被引：134
作者：
Kusari, Souvik [1 ]
Spiteller, Michael [1 ]
机构：
[1] TU Dortmund, Chair Environm Chem & Analyt Chem, Fac Chem, Inst Environm Res INFU, D-44221 Dortmund, Germany
来源：
NATURAL PRODUCT REPORTS | 2011年 / 28卷 / 07期
关键词：
HORIZONTAL GENE-TRANSFER; HYPERICUM-PERFORATUM; NATURAL-PRODUCTS; DRUG DISCOVERY; FUNGUS; PODOPHYLLOTOXIN; MICROORGANISMS; BIOSYNTHESIS; BIODIVERSITY; DIVERSITY;
D O I：
10.1039/c1np00030f
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The prospect of endophytes capable of producing associated plant natural products with therapeutic potential is undeniable. However, the unyielding struggle so far to transform these potential sources into sustainable microbial manufacturers on a commercial scale has been disappointing. In this Viewpoint, we address this trade-off between endophyte discovery and viable industrial application.
引用
收藏
页码：1203 / 1207
页数：5
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