Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver

被引:66
作者
He, Bingbing [1 ,3 ]
Peng, Wenbo [2 ,3 ]
Huang, Jia [1 ,3 ]
Zhang, Hang [2 ]
Zhou, Yingsi [1 ]
Yang, Xiali [1 ]
Liu, Jing [4 ]
Li, Zhijie [2 ,3 ]
Xu, Chunlong [1 ]
Xue, Mingxing [1 ]
Yang, Hui [1 ]
Huang, Pengyu [2 ,5 ]
机构
[1] Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai Res Ctr Brain Sci & Brain Inspired Intel, Inst Neurosci,Shanghai Inst Biol Sci,State Key La, Shanghai 200031, Peoples R China
[2] ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
[3] Univ Chinese Acad Sci, Coll Life Sci, Beijing 100049, Peoples R China
[4] Chinese Acad Agr Sci, Agr Genome Inst Shenzhen, Ctr Anim Genom, Shenzhen 518124, Peoples R China
[5] Chinese Acad Sci, CAS Ctr Excellence Mol Cell Sci, Shanghai 200031, Peoples R China
基金
中国国家自然科学基金;
关键词
CHOLESTEROL; TARGET; PCSK9; RNA;
D O I
10.1007/s13238-020-00700-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:518 / 524
页数:7
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