Ankyrin for methylated lysines

被引：12
作者：
Brent, Michael M. [1 ,2 ]
Marmorstein, Ronen [1 ,2 ]
机构：
[1] Univ Penn, Wistar Inst, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2008年 / 15卷 / 03期
关键词：
D O I：
10.1038/nsmb0308-221
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The ankyrin repeats of the G9a and GLP histone methyltransferases have now been shown to be binding modules for mono- and dimethyllysine histone H3 lysine 9 (H3K9), revealing a new function for an ankyrin repeat domain and showing that a polypeptide chain can both create and recognize the same histone mark.
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收藏
页码：221 / 222
页数：2
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