Palladium-Catalyzed [5+1] Annulation of 2-(1-Arylvinyl) Anilines and α-Diazocarbonyl Compounds toward Multi-functionalized Quinolines

被引：35

作者：

Zhu, Jiawei ^{[1
]}

Hu, Weiming ^{[1
]}

Sun, Song ^{[1
]}

Yu, Jin-Tao ^{[1
]}

Cheng, Jiang ^{[1
]}

机构：

[1] Changzhou Univ, Jiangsu Prov Key Lab Fine Petrochem Engn, Jiangsu Key Lab Adv Catalyt Mat & Technol, Sch Petrochem Engn, Changzhou 213164, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2017年 / 359卷 / 21期

基金：

中国国家自然科学基金;

关键词：

palladium-catalyzed; annulation; alpha-diazocarbonyl compounds; 2,4-aryl quinolines; AEROBIC OXIDATION CATALYSIS; ALCOHOLIC OXONIUM YLIDE; 3-COMPONENT REACTION; N-TOSYLHYDRAZONES; DIAZO-COMPOUNDS; COORDINATED PALLADIUM(0); SUBSTITUTED QUINOLINES; ARYL DIAZOACETATES; CARBONYL-COMPOUNDS; MOLECULAR-OXYGEN;

D O I：

10.1002/adsc.201701069

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A palladium-catalyzed [5+1] annulation of 2-(1-arylvinyl) anilines and alpha-diazocarbonyl compounds has been developed, affording a series of multi-functionalized quinolines in moderate to good yields. This procedure proceeded with the sequential insertion of N-H bond to the palladium carbene, intramolecular Heck reaction and decarboxylation steps. In this reaction, alkyl 2-diazophenylacetates served as C1 building block, which represents a key compliment to diazo chemistry.

引用

页码：3725 / 3728

页数：4

共 47 条

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