Biosynthesis of Beta vulgaris mediated ZnO Nanoparticles and their Anti-bacterial, Anti-fungal, Anti-diabetic and Anti-cancer Activities

被引：5
作者：
Femina, F. [1 ]
Thabassoom, H. Asia [1 ]
Ruby, S. Auxilia [1 ]
Florence, J. Felicita [1 ]
机构：
[1] Bharathidasan Univ, Holy Cross Coll Autonomous, Tiruchirappalli 620002, Tamil Nadu, India
来源：
ORIENTAL JOURNAL OF CHEMISTRY | 2021年 / 37卷 / 04期
关键词：
Beta vulgaris; Phytochemical analysis; Zinc nanoparticles; Anti-bacterial; Anti-fungal activity; Anti-diabetic activity; Anti-cancer activity; ZINC-OXIDE NANOPARTICLES; GREEN SYNTHESIS; LEAF EXTRACT; ANTIOXIDANT; CANCER; RED;
D O I：
10.13005/ojc/370420
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Plant extract mediated metal or metal oxide nanoparticles is a promising alternate to the chemical and physical methods. Application of nanoparticles in various fields get increased widely due to their properties. Current study involves the eco-friendly method of synthesis and pharmacological applications of zinc oxide nanoparticles (ZnO-NPs) using the aqueous beetroot (Beta vulgaris) extract. Aqueous Beta vulgaris extract has multiple bio-active phytochemicals especially antioxidants like anthocyanins and betacyanins, also reported a rich source of minerals. Synthesized ZnONPs were characterized with the aid of UV-Vis spectroscopy, FTIR, SEM, XRD and EDX. Antibacterial results suggests that, Beta vulgaris mediated ZnONPs possessthe maximum zone of inhibition against Escherichia colithen Staphylococcus aureus. On anti-fungal activity synthesized ZnONPS revealed greater inhibitory effect against Candida albicans fungi than the Aspergillus flavus. Synthesized ZnONPs exhibits the noticeable pharmacological activities against the anti-diabetic and anti-cancer activities (MCF-7 cell line, IC50=35.4 mu g/mL). This study has suggested an effective replacement for the hazardous chemical methods and lead to a cost-effective, environmentally-friendly method which can also be used as an antimicrobial, anti-diabetic and anti-cancer agents.
引用
收藏
页码：911 / 921
页数：11
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