How microRNAs choose their targets

被引：41
作者：
Hofacker, Ivo L. [1 ]
机构：
[1] Univ Vienna, Inst Theoret Chem, A-1090 Vienna, Austria
来源：
NATURE GENETICS | 2007年 / 39卷 / 10期
关键词：
D O I：
10.1038/ng1007-1191
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The growing list of known microRNAs is only as useful as our ability to identify the mRNA targets they control. A new study stresses the role of messenger RNA structure in microRNA target recognition and suggests that binding of the RNA-induced silencing complex is largely controlled by the thermodynamics of RNA-RNA interactions.
引用
收藏
页码：1191 / 1192
页数：3
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