How microRNAs choose their targets

被引：41

作者：

Hofacker, Ivo L. ^{[1
]}

机构：

[1] Univ Vienna, Inst Theoret Chem, A-1090 Vienna, Austria

来源：

NATURE GENETICS | 2007年 / 39卷 / 10期

关键词：

D O I：

10.1038/ng1007-1191

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The growing list of known microRNAs is only as useful as our ability to identify the mRNA targets they control. A new study stresses the role of messenger RNA structure in microRNA target recognition and suggests that binding of the RNA-induced silencing complex is largely controlled by the thermodynamics of RNA-RNA interactions.

引用

页码：1191 / 1192

页数：3

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