Transition Metal-Free trans-Selective Alkynylboration of Alkynes

被引：46

作者：

Nogami, Marina ^{[1
]}

Hirano, Keiichi ^{[1
]}

Kanai, Misae ^{[2
,3
]}

Wang, Chao ^{[1
]}

Saito, Tatsuo ^{[1
]}

Miyamoto, Kazunori ^{[1
]}

Muranaka, Atsuya ^{[2
,3
]}

Uchiyama, Masanobu ^{[1
,2
,3
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

[2] RIKEN, Adv Elements Chem Res Team, Ctr Sustainable Resource Sci, 2-1 Hirosawa, Wako, Saitama 3510198, Japan

[3] RIKEN, Elements Chem Lab, 2-1 Hirosawa, Wako, Saitama 3510198, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 36期

关键词：

REGIOSELECTIVE FORMAL HYDROBORATION; BORON-CONTAINING COMPOUNDS; CROSS-COUPLING REACTIONS; CATALYZED ADDITION; ARYLBORONIC ACIDS; ORGANOBORON COMPOUNDS; ANTI-CARBOBORATION; FREE DIBORATION; ARYL HALIDES; BORYLATION;

D O I：

10.1021/jacs.7b06212

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the first transition metal-free and trans-selective alkynylboration reaction of alkynes. This unprecedented carboboration reaction is enabled by pseudo-intramolecular activation of alkynylboronates using propargylic alcohols. The carboboration affords 4-alkynyl-1,2-oxaborol-2(5H)-ols, which are not only versatile building blocks but also exhibit strong violet blue fluorescence emission.

引用

页码：12358 / 12361

页数：4

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