Sensitive Detection of Hg2+ with Switchable Electrochemiluminescence Luminophore and Disposable Bipolar Electrode

被引：14
作者：
Liu, Hongxing [1 ,2 ]
Zhou, Xiaoming [1 ,2 ]
Shen, Jinjin [1 ,2 ]
Xing, Da [1 ,2 ]
机构：
[1] South China Normal Univ, MOE Key Lab Laser Life Sci, Guangzhou 510631, Guangdong, Peoples R China
[2] South China Normal Univ, Inst Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
来源：
CHEMELECTROCHEM | 2017年 / 4卷 / 07期
基金：
中国国家自然科学基金;
关键词：
electrochemiluminescence; label-free detection; light-switch" molecules; mercury ions; paper-based bipolar electrodes; MERCURY; NANOCLUSTERS; SPECTROMETRY; FLUORESCENT; CADMIUM; URINE; LEAD; DNA;
D O I：
10.1002/celc.201600912
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
A novel paper-based bipolar electrode-electrochemiluminescence (pBPE-ECL) switch system was used for the rapid, label-free, and sensitive detection of Hg2+. In the proposed approach, Hg2+ selectively mediates two thymine-enriched single-stranded DNA probes to form double-stranded DNA (dsDNA). In the presence of Hg2+, the "light-switch" molecule [Ru(phen)(2) dppz](2+) can freely intercalate into the base pairs of the dsDNA, resulting in intense ECL emission. The assay takes advantage of the wireless pBPE-ECL platform to yield a low-cost, disposable, and sensitive analysis. The system has a limit of 0.1 nM for Hg2+ detection. We also showed that the system can be used to distinguish Hg2+ over other metal ions, including Pb2+, Zn2+, Cu2+, Ba2+, Co2+, Cd2+, Fe3+, Mn2+, and Li+. Moreover, the proposed approach was rapid, low-cost, and label-free for effective sensing of Hg2+ in drinking and lake water.
引用
收藏
页码：1681 / 1685
页数：5
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