Protracted anaphylaxis developed after peginterferon α-2a administration for chronic hepatitis C

被引：7

作者：

Sakatani, Akihiko ^{[1
]}

Doi, Yoshinori ^{[2
]}

Matsuda, Takaaki ^{[2
]}

Sasai, Yasutaka ^{[2
]}

Nishida, Naohiro ^{[2
]}

Sakamoto, Megumi ^{[2
]}

Uenoyama, Naoto ^{[2
]}

Matsumoto, Yoshiya ^{[3
]}

Kinoshita, Kazuo ^{[2
]}

机构：

[1] Osaka Univ, Grad Sch Med, Dept Gastroenterol & Hepatol, Suita, Osaka 5650871, Japan

[2] Otemae Hosp, Dept Gastroenterol, Osaka 5400008, Japan

[3] Otemae Hosp, Dept Resp Med, Osaka 5400008, Japan

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2015年 / 21卷 / 09期

关键词：

Peginterferon alpha-2a; Anaphylaxis; Anaphylactic shock; Protracted anaphylaxis; Chronic hepatitis C; INTERFERON; THERAPY;

D O I：

10.3748/wjg.v21.i9.2826

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Peginterferon is a key drug used to treat chronic viral hepatitis that is known for causing various side effects. Side effects occurring immediately after administration include headache, nausea, and influenza-like symptoms, such as fever and joint pain. However, reports of anaphylactic shock are extremely rare. Here we report a patient with protracted anaphylaxis who suffered shock symptoms after peginterferon alpha-2a administration for chronic hepatitis C. Although the patient improved temporarily with shock treatment, symptoms of anaphylaxis recurred. As peginterferon is often administered on an outpatient basis, it is important to recognize life-threatening side effects that may develop in a protracted manner.

引用

页码：2826 / 2829

页数：4

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