Bisphosphonate-related atypical femoral fracture: Managing a rare but serious complication

被引:15
作者
Silverman, Stuart [1 ,2 ,3 ]
Kupperman, Eli [4 ]
Bukata, Susan [5 ]
机构
[1] Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA
[2] OMC Clin Res Ctr, Beverly Hills, CA USA
[3] UCLA, David Geffen Sch Med, Med, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, Dept Orthopaed Surg, Los Angeles, CA USA
[5] UCLA, David Geffen Sch Med, Los Angeles, CA 90095 USA
关键词
FEMUR FRACTURES; SHAFT FRACTURES; HIP FRACTURE; OLDER-ADULTS; RISK; WOMEN; MORTALITY; OUTCOMES; THERAPY; ALENDRONATE;
D O I
10.3949/ccjm.85a.17119
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Atypical femoral fracture is a rare but serious complication of long-term bisphosphonate therapy. Although the benefit of preventing osteoporotic fractures greatly outweighs the risk of atypical fracture in bisphosphonate users, concern about atypical fracture risk has led to a decrease in bisphosphonate use. What are the risks, and how do we treat atypical femoral fracture?
引用
收藏
页码:885 / 893
页数:9
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