Psychometric validation of a sexual quality of life questionnaire for use in men with premature ejaculation or erectile dysfunction

被引:113
作者
Abraham, Lucy [1 ]
Psychol, C. [1 ]
Symonds, Tara [2 ]
Morris, Mark F. [2 ]
机构
[1] Pfizer Ltd, Global Outcomes Res Ipc 160, Sandwich CT13 9NJ, Kent, England
[2] Pfizer Ltd, Clin Stat, Sandwich CT13 9NJ, Kent, England
关键词
sexual quality of life; men; erectile dysfunction; premature ejaculation;
D O I
10.1111/j.1743-6109.2007.00749.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
An instrument that can systematically capture the impact of sexual dysfunction on quality of life (QoL) in men is needed. To psychometrically validate a sexual QoL instrument for men (SQOL-M) with premature ejaculation (PE) or erectile dysfunction (ED). The main assessment populations were men participating in clinical trials of treatments for PE or ED. Men with PE had a confirmed intravaginal ejaculatory latency time of <= 2 minutes in >= 70% of attempts. Men with ED had a score of > 21 on the International Index of Erectile Function (IIEF). Confirmatory psychometric testing was conducted in further groups of men with PE. The internal consistency, convergent and discriminant validity, test-retest reliability, and known-groups validity of the instrument were assessed. An 11-item version of the SQOL-M was produced following factor analyses on men with either PE or ED. Psychometric testing showed no overlap between items and good item-total correlations. Factor analysis confirmed a one-factor solution. Excellent internal consistency was demonstrated, with a Cronbach's alpha of >= 0.82 in all groups. In men reporting no change in their symptoms, the SQOL-M showed excellent test-retest reliability: the intraclass correlation coefficient was 0.77 for men with PE, and 0.79 for men with ED. Convergent validity was also good. In men with PE, the SQOL-M correlated with the satisfaction and distress domains of the Index of Premature Ejaculation. In men with ED, the SQOL-M correlated with the overall satisfaction domain of the IIEF. The measure also demonstrated excellent discriminant validity between men with PE or ED and men with no sexual dysfunction (P < 0.0001). The SQOL-M instrument is a useful tool for evaluating sexual QoL in men with PE and ED.
引用
收藏
页码:595 / 601
页数:7
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