Intimal Sarcoma of the Pulmonary Artery Treated with Pazopanib

被引：17

作者：

Funatsu, Yohei ^{[1
]}

Hirayama, Miwa ^{[1
]}

Shiraishi, Junichi ^{[2
]}

Asakura, Takanori ^{[1
]}

Wakaki, Misa ^{[1
]}

Yamada, Erina ^{[1
]}

Fujimoto, Kazuyuki ^{[1
]}

Satomi, Ryosuke ^{[1
]}

Inaki, Shunsuke ^{[1
]}

Murata, Yuya ^{[2
]}

Oyamada, Yoshitaka ^{[1
]}

机构：

[1] Tokyo Med Ctr, Natl Hosp Org, Resp Med, Tokyo, Japan

[2] Tokyo Med Ctr, Natl Hosp Org, Pathol, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2016年 / 55卷 / 16期

关键词：

intimal sarcoma of the pulmonary artery; pazopanib; disease flare; tyrosine kinase inhibitor; ACQUIRED-RESISTANCE; DISEASE FLARE; LUNG-CANCER; TUMORS; DISCONTINUATION; THERAPY; TRIAL;

D O I：

10.2169/internalmedicine.55.6199

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Intimal sarcoma is a rare disease with a poor prognosis. We herein report the case of a 71-year-old man with intimal sarcoma of the pulmonary artery treated with pazopanib. The tumor showed regression after 1 month of treatment. Hand-foot syndrome led to cessation of pazopanib, which triggered a disease flare. Pazopanib should be considered in patients with intimal sarcoma of the pulmonary artery that is unresectable or recurrent after surgery or cytotoxic chemotherapy. We must be careful about drug cessation, as it can lead to a disease flare.

引用

页码：2197 / 2202

页数：6

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