ONE-POT GREEN SYNTHESIS OF NOVEL POLYSUBSTITUTED 1,2-DIHYDRONAPHTHO[2,1-b]FURANS

被引:13
作者
Sadeghpour, Mandieh [1 ]
Olyaei, Abolfazl [2 ]
Lotfiyan, Jamshid [2 ]
Rajabi, Fatemeh [2 ]
机构
[1] Islamic Azad Univ, Takestan Branch, Dept Chem, Takestan, Iran
[2] PNU, Dept Chem, Tehran, Iran
关键词
1,2-Dihydronaphtho[2,1-b]furans; 2-aminopyridines; glyoxal; naphthol; SOLVENT; REARRANGEMENT; INHIBITORS; BASES;
D O I
10.1080/00397911.2015.1017052
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple and highly efficient one-pot protocol for the synthesis of novel polysubstituted 1,2-dihydronaphtho[2,1-b] furans has been developed by three-component coupling reaction of 2-aminopyridines, naphthols, and glyoxal in the presence of guanidinium chloride as a polyfunctional organocatalyst under solvent-free conditions. The protocol avoids the use of expensive catalysts, toxic solvents, and chromatographic separation and provides a wide range of novel dihydronaphthofurans in good to excellent yields.
引用
收藏
页码:1311 / 1320
页数:10
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