Snaclecs (snake C-type lectins) that inhibit or activate platelets by binding to receptors

被引：103
作者：
Clemetson, Kenneth J. [1 ]
机构：
[1] Univ Bern, Dept Haematol, Inselspital, CH-3010 Bern, Switzerland
来源：
TOXICON | 2010年 / 56卷 / 07期
关键词：
Platelets; Receptors; C-type lectins; Snaclecs; Snake venom; VON-WILLEBRAND-FACTOR; AGKISTRODON-ACUTUS VENOM; HABU TRIMERESURUS-MUCROSQUAMATUS; CROTALUS-DURISSUS-TERRIFICUS; AGGREGATION-INDUCING FACTOR; GLYCOPROTEIN IB-ALPHA; AMINO-ACID-SEQUENCE; MALAYAN PIT VIPER; SAW-SCALED VIPER; JARARACA GPIB-BP;
D O I：
10.1016/j.toxicon.2010.03.011
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
More than 300 known species of venomous snakes are classified into five families, Hydrophidae, Elapidae, Viperidae, Crotalidae and Colubidae. Venom proteins have also been demonstrated recently in other snakes and some lizards (Fry et al., 2006). Venom components that affect hemostasis are most generally found in Viperidae, and Crotalidae snakes but the others often contain some as well. This review concentrates on structural and functional properties of venom components of the C-type lectin related class (now named snaclecs) that inhibit or activate platelets by binding to receptors. (C) 2010 Elsevier Ltd. All rights reserved.
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收藏
页码：1236 / 1246
页数：11
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