Mycophenolate mofetil for myasthenia gravis: An open-label pilot study

被引：124

作者：

Ciafaloni, E ^{[1
]}

Massey, JM ^{[1
]}

Tucker-Lipscomb, B ^{[1
]}

Sanders, DB ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Div Neurol, Durham, NC 27710 USA

来源：

NEUROLOGY | 2001年 / 56卷 / 01期

关键词：

D O I：

10.1212/WNL.56.1.97

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In an open-label study, 12 patients with refractory MG or who were taking only corticosteroids and required additional immunosuppression received mycophenolate mofetil 1 g twice daily for 6 months. A reduction of three points in a quantified MG score and two points in a manual muscle test or a reduction of 50% in corticosteroid dose defined efficacy. Eight patients improved, beginning after 2 weeks to 2 months. No major side effects were observed.

引用

页码：97 / 99

页数：3

共 9 条

[1]

Allison AC, 1996, CLIN TRANSPLANT, V10, P77

[2]

ALLISON AC, 1994, TRANSPLANT P, V26, P3205

[3] Reliability testing of the quantitative myasthenia gravis score [J].