Olfactory and intranasal trigeminal event-related potentials in anosmic patients

被引:92
作者
Kobal, G
Hummel, T
机构
[1] Tech Univ Dresden, Dept Otorhinolaryngol, D-01307 Dresden, Germany
[2] Univ Erlangen Nurnberg, Dept Expt & Clin Pharmacol & Toxicol, D-8520 Erlangen, Germany
[3] Univ Penn, Med Ctr, Ctr Smell & Taste, Dept Otolaryngol Head & Neck Surg, Philadelphia, PA 19104 USA
关键词
olfaction; anosmia; trigeminal nerve; irritation;
D O I
10.1097/00005537-199807000-00015
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The aim of this study was to investigate the usefulness of chemosensory event-related potentials (CSERPs) in response to both olfactory and intranasal trigeminal stimulation in the diagnosis of anosmia. Forty-four patients participated. Gaseous CO2 was used for trigeminal stimulation, vanillin and H2S were used as olfactory stimulants. Event-related potentials to olfactory stimuli could not be obtained in any of the anosmic patients, indicating the complete loss of the sense of smell. However, all patients responded to stimulation of the trigeminal nerve with CO2, These data clearly demonstrate the clinical significance of CSERPs in the assessment of anosmia.
引用
收藏
页码:1033 / 1035
页数:3
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