An isomerization-ring-closing metathesis strategy for the synthesis of substituted benzofurans

被引:92
|
作者
van Otterlo, WAL [1 ]
Morgans, GL [1 ]
Madeley, LG [1 ]
Kuzvidza, S [1 ]
Moleele, SS [1 ]
Thornton, N [1 ]
de Koning, CB [1 ]
机构
[1] Univ Witwatersrand, Mol Sci Inst, Sch Chem, ZA-2050 Johannesburg, South Africa
基金
新加坡国家研究基金会; 美国安德鲁·梅隆基金会;
关键词
benzofurans; isomerization; ring-closing metathesis;
D O I
10.1016/j.tet.2005.05.090
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Twelve substituted benzofurans were synthesized from their corresponding substituted l-allyl-2-allyloxybenzenes using ruthenium-mediated G and O-allyl isomerization followed by ring-closing metathesis. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7746 / 7755
页数:10
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