Apigenin inhibits tumor necrosis factor α-induced cell proliferation and prostaglandin E2 synthesis by inactivating NFκB in endometriotic stromal cells

被引：22
作者：
Suou, Kana [1 ]
Taniguchi, Fuminori [1 ]
Tagashira, Yukiko [1 ]
Kiyama, Tomoiki [1 ]
Terakawa, Naoki [1 ]
Harada, Tasuku [1 ]
机构：
[1] Tottori Univ, Fac Med, Dept Obstet & Gynecol, Yonago, Tottori 6838504, Japan
来源：
FERTILITY AND STERILITY | 2011年 / 95卷 / 04期
关键词：
Apigenin; endometriosis; NFkB; NITRIC-OXIDE SYNTHASE; PERITONEAL-FLUID; EXPRESSION; CYCLOOXYGENASE-2; INTERLEUKIN-8; FLAVONOIDS; INDUCTION; MACROPHAGES; ACTIVATION; APOPTOSIS;
D O I：
10.1016/j.fertnstert.2010.09.046
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Apigenin suppressed tumor necrosis factor a-induced cell proliferation and prostaglandin E2 expression via the attenuation of nuclear factor kappa B pathway in endometriotic stromal cells in vitro. Apigenin reduced the mitogenic activity and inflammatory reaction in endometriotic stromal cells. (Fertil Steril (R) 2011;95:1518-21. (C) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码：1518 / 1521
页数：4
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