The measurement of vitamin D metabolites part II-the measurement of the various vitamin D metabolites

被引：13
|
作者：
Makris, Konstantinos [1 ]
Sempos, Christopher [2 ]
Cavalier, Etienne [3 ]
机构：
[1] KAT Gen Hosp, Clin Biochem Dept, 2 Nikis Str, Kifisia 14561, Greece
[2] VDSP, Havre De Grace, MD 21078 USA
[3] Univ Liege, Dept Clin Chem, CHU Liege, Liege, Belgium
来源：
HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM | 2020年 / 19卷 / 02期
关键词：
Vitamin D; 1; alpha; 25-dihydroxy-vitamin D; 24,25-dihydroxy-vitamin D; C3-epimers; Vitamin D-binding protein; Free vitamin D; Bioavailable vitamin D; D-BINDING-PROTEIN; SERUM 24,25-DIHYDROXYVITAMIN D; 25-HYDROXYVITAMIN D LEVELS; LIQUID-CHROMATOGRAPHY; MASS-SPECTROMETRY; LC-MS/MS; CALCITRIOL CONCENTRATIONS; CYP24A1; MUTATIONS; KIDNEY-DISEASE; GC-GLOBULIN;
D O I：
10.1007/s42000-020-00188-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Today, the possibility exists to measure a number of different vitamin D metabolites with accurate and precise methods. The most abundant vitamin D metabolite, 25(OH)D, is considered the best marker for estimating vitamin D status and is therefore the most commonly measured in clinical practice. There is no consensus on the added value of measuring other metabolites beyond 25-hydroxyvitamin D, although, in some special clinical scenarios and complicated cases, these metabolites may provide just the information needed for an accurate diagnosis. The problem this review addresses is which metabolite to measure and when and how to measure it.
引用
收藏
页码：97 / 107
页数：11
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