HPLC analyses of H-2 receptor antagonist products (Ranitidine, cimetidine and famotidine)

被引：0
|
作者：
Ashnagar, A. [1 ]
Naseri, N. Gharib [1 ]
Kavoosi, M. [1 ]
机构：
[1] Ahwaz Jundi Shapour Univ Med Sci, Sch Pharm, Ahvaz, Iran
来源：
ASIAN JOURNAL OF CHEMISTRY | 2007年 / 19卷 / 07期
关键词：
ranitidine; cimetidine; famotidine; H-2 receptor antagonist; histamine H-2-blocker;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this research, the purity of the standard active ingredients of the tablets (ranitidine, cimetidine and famotidine) imported from abroad and the purity percentage of the active ingredients in each of the H-2 receptor antagonist tablets manufactured by several pharmaceutical companies of Iran were investigated and determined by HPLC technique. The analyses were made by using a 30 cm Finepak sil C8-5 column. A 20 mu L solution from each individual sample and the standard solution were injected separately onto the column of an HPLC instrument which was equipped with ECW2000 software. The results obtained in this research have shown that with the exception of cimetidine tablets manufactured by Lorestan pharmaceutical company, all other tablets used in this research and manufactured in Iran can satisfy the needs of patients. Also, the imported standard powders were 100 % pure.
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页码：5555 / 5561
页数：7
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