The enantiospecific total synthesis of norsuaveoline

被引:23
作者
Wang, T [1 ]
Yu, P [1 ]
Li, J [1 ]
Cook, JM [1 ]
机构
[1] Univ Wisconsin, Dept Chem, Milwaukee, WI 53201 USA
关键词
D O I
10.1016/S0040-4039(98)01788-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Norsuaveoline 1a has been synthesized enantiospecifically in 28% overall yield from commercially available D-(+)-tryptophan methyl ester via the asymmetric Pictet-Spengler reaction and a stereocontrolled oxy-anion Cope rearrangement as key steps. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:8009 / 8012
页数:4
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