Sequential N-acylamide methylenation-enamide ring-closing metathesis:: a synthetic entry to 1,4-dihydroquinolines

被引：39

作者：

Bennasar, ML ^{[1
]}

Roca, T ^{[1
]}

Monerris, M ^{[1
]}

García-Díaz, D ^{[1
]}

机构：

[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 23期

关键词：

dimethyltitanocene; olefination; enamides; ring-closing metathesis; 1,4-dihydroquinolines;

D O I：

10.1016/j.tetlet.2005.04.028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic entry to the 1,4-dihydroquinoline nucleus is reported. The procedure involves the dimethyltitanocene methylenation of N-(alkoxycarbonyl)amides derived from 2-allylanilines, followed by ring-closing metathesis of the resulting enamides. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4035 / 4038

页数：4

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