Atopic dermatitis: phototherapy and systemic therapy

被引：5

作者：

Davis, Dawn Marie ^{[1
]}

Borok, Jenna ^{[2
,3
,4
]}

Udkoff, Jeremy ^{[2
,3
,4
]}

Lio, Peter ^{[5
,6
,7
]}

Spergel, Jonathan ^{[8
]}

机构：

[1] Mayo Clin, Dept Dermatol & Pediat, Rochester, MN 55902 USA

[2] Rady Childrens Hosp, Div Pediat & Adolescent Dermatol, San Diego, CA USA

[3] Univ Calif San Diego, Sch Med, Dept Dermatol, La Jolla, CA 92093 USA

[4] Univ Calif San Diego, Sch Med, Dept Pediat, La Jolla, CA 92093 USA

[5] Northwestern Univ, Feinberg Sch Med, Dept Dermatol, Chicago, IL 60611 USA

[6] Northwestern Univ, Feinberg Sch Med, Dept Pediat, Chicago, IL 60611 USA

[7] Med Dermatol Associates Chicago, Chicago, IL USA

[8] Univ Penn, Div Allergy & Immunol, Childrens Hosp Philadelphia, Dept Pediat,Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

SEMINARS IN CUTANEOUS MEDICINE AND SURGERY | 2017年 / 36卷 / 03期

基金：

美国国家卫生研究院;

关键词：

RANDOMIZED CONTROLLED-TRIAL; DOUBLE-BLIND; THIOPURINE METHYLTRANSFERASE; PRACTICE PARAMETER; CYCLOSPORINE-A; AZATHIOPRINE; ECZEMA; METHOTREXATE; ADULT; PLACEBO;

D O I：

10.12788/j.sder.2017.027

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The majority of atopic dermatitis (AD) patients respond satisfactorily to gentle bathing, frequent moisturizing, and topical medications. Second-line therapies for AD should be used in recalcitrant cases or in patients with uncontrolled disease despite compliance with first-line measures and avoidance of allergens. Recommended advanced therapies include phototherapy, especially narrowband ultraviolet B, systemic immunosuppressants, and a new biologic agent. Few studies have compared head-to-head efficacy of the different immunosuppressant therapies such as cyclosporine, methotrexate, azathioprine and mycophenolate mofetil.Therefore, the agent used is based on provider and patient preferences and can be decided on a case-by-case basis. (C) 2017 Frontline Medical Communications

引用

页码：118 / 123

页数：6

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