A Natural Cattle Immune Response Against Horn Fly (Diptera: Muscidae) Salivary Antigens May Regulate Parasite Blood Intake

被引：5

作者：

Breijo, M. ^{[1
]}

Pastro, L. ^{[2
]}

Rocha, S. ^{[1
]}

Ures, X. ^{[1
]}

Alonzo, P. ^{[1
]}

Santos, M. ^{[1
]}

Bolatto, C. ^{[3
]}

Fernandez, C. ^{[4
]}

Meikle, A. ^{[5
]}

机构：

[1] Univ Republica, Fac Med, Unidad React & Biomodelos Expt, Gral Flores 2125, Montevideo, Uruguay

[2] Fac Ciencias, Lab Interacc Mol, Igua 4225, Montevideo 11400, Uruguay

[3] Univ Republica, Fac Med, Dept Histol & Embriol, Gral Flores 2125, Montevideo, Uruguay

[4] Univ Republica, Inst Higiene, Fac Quim, Catedra Inmunol, Av Alfredo Navarro 3051, Montevideo 11600, Uruguay

[5] Univ Republica, Fac Vet, Lab Tecn Nucl, Lasplaces 1550, Montevideo, Uruguay

来源：

JOURNAL OF ECONOMIC ENTOMOLOGY | 2016年 / 109卷 / 04期

关键词：

H; irritans; blood feeding; cattle; salivary antigen; antibody response; HAEMATOBIA-IRRITANS DIPTERA; ANTIBODY-RESPONSE; STABLE FLY; GLAND; POPULATION; DYNAMICS; VACCINE;

D O I：

10.1093/jee/tow133

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

The horn fly, Haematobia irritans (L.), is a blood-sucking ectoparasite that is responsible for sizeable economic losses in livestock. The salivary gland products facilitate blood intake. Taking advantage of the identification of novel H. irritans salivary antigens (Hematobin, HTB and Irritans 5, IT5), we investigated the parasite loads, H. irritans blood intake, and antibody response of naturally infected bovines during the fly season. Fly loads and fly hemoglobin content fluctuated during the trial. Each time horn fly loads exceeded 200 flies per cattle, a reduction in horn fly blood intake was observed three weeks later. All of the cattle elicited an antibody response against HTB and IT5 that declined once the fly season was over. Cattle anti-IT5 titers were positively correlated with parasite loads and negatively correlated with fly blood intake. These results suggest that the natural changes in the H. irritans blood intake observed in this study were associated with a natural host response against horn fly salivary antigens.

引用

页码：1951 / 1956

页数：6