Bin classification of G-protein-coupled peptide receptors

被引：0

作者：

Moereels, H ^{[1
]}

Lewi, PJ ^{[1
]}

Daeyaert, F ^{[1
]}

Janssen, PAJ ^{[1
]}

机构：

[1] Janssen Res Fdn, Ctr Mol Design, B-2350 Vosselaar, Belgium

来源：

LETTERS IN PEPTIDE SCIENCE | 1998年 / 5卷 / 2-3期

关键词：

binmap; counting residues; sequence consistency;

D O I：

10.1007/BF02443456

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

With the use of the binmap method, 154 G-protein-coupled peptide receptors are classified. The binmap coordinates are obtained by using the number of residues between the conserved N residue in TM1 and C in the TM4-TM5 loop, between this C and the conserved P in TM6, and between this P and the last residue of the sequence. The binmap suggests that the cloned fMLP receptor in rabbit belongs in fact to the IL8 receptor type.

引用

页码：139 / 142

页数：4

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