Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis

被引：112

作者：

Parks, Tom ^{[1
]}

Wilson, Clare ^{[2
]}

Curtis, Nigel ^{[3
]}

Norrby-Teglund, Anna ^{[4
]}

Sriskandan, Shiranee ^{[2
]}

机构：

[1] London Sch Hyg & Trop Med, London, England

[2] Imperial Coll London, London, England

[3] Royal Childrens Hosp, Melbourne, Vic, Australia

[4] Karolinska Inst, Stockholm, Sweden

来源：

CLINICAL INFECTIOUS DISEASES | 2018年 / 67卷 / 09期

基金：

英国医学研究理事会;

关键词：

Group A streptococcus; Streptococcus pyogenes; intravenous immunoglobulin; streptococcal toxic shock syndrome; necrotising fasciitis; THERAPY; INFECTIONS; DISEASE;

D O I：

10.1093/cid/ciy401

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.

引用

页码：1434 / 1436

页数：3