Nef-Perkow Access to Indolizine Derivatives

被引：26
作者：
Coffinier, Didier [1 ]
El Kaim, Laurent [1 ]
Grimaud, Laurence [1 ]
机构：
[1] Ecole Natl Super Tech Avancees, Lab Chim & Procedes, F-75739 Paris 15, France
来源：
SYNLETT | 2010年 / 16期
关键词：
Nef reaction; isocyanide; indolizine; pyridinium ylide; cycloaddition; MULTICOMPONENT REACTIONS; CYCLOADDITION REACTIONS; 1,3-DIPOLAR CYCLOADDITION; HETEROCYCLE SYNTHESIS; AZOMETHINE YLIDES; POTENT INHIBITORS; AB-INITIO; ISOCYANIDES; KETENIMINES; PYRIDINIUM;
D O I：
10.1055/s-0030-1258569
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We present herein a new access to indolizine derivatives involving 1,3-dipolar cycloaddition of pyridinium ylides with phosphorylated hydroxyketenimines. These ketenimines are easily formed via a Nef-Perkow cascade involving isocyanides as starting material.
引用
收藏
页码：2474 / 2476
页数：3
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