A turn-on chemosensor for Hg2+ in aqueous media and its application in "MCT" imaging in living cells

被引:21
作者
Xi, Pinxian [1 ,2 ]
Huang, Liang [1 ,2 ]
Xie, Guoqiang [1 ,2 ]
Chen, Fengjuan [1 ,2 ]
Xu, Zhihong [3 ]
Bai, Decheng [4 ]
Zeng, Zhengzhi [1 ,2 ]
机构
[1] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China
[3] Xuchang Univ, Coll Chem & Chem Engn, Xuchang 461000, Peoples R China
[4] Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Peoples R China
关键词
FLUORESCENT CHEMOSENSOR; MERCURY; CU(II); SENSOR; ION; FLUOROIONOPHORE; CHROMOIONOPHORE; RECOGNITION; ETHER; PROBE;
D O I
10.1039/c1dt10573f
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A turn-on chemosensor L1, which exhibits high selectivity and sensitivity toward Hg2+ over other common metal ions in aqueous media under a physiological pH window via a 1:1 binding mode, had been synthesized and characterized. L1 provides good fluorescent imaging of Hg2+ in living cells. Particularly, we adopted the "micro computed tomography (MCT)" technology, successfully demonstrating the method of Hg2+ sensing by L1 in cell lines, also the cell permeability of L1 and its imaging position in the cells.
引用
收藏
页码:6382 / 6384
页数:3
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