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A turn-on chemosensor for Hg2+ in aqueous media and its application in "MCT" imaging in living cells
被引:21
作者:
Xi, Pinxian
[1
,2
]
Huang, Liang
[1
,2
]
Xie, Guoqiang
[1
,2
]
Chen, Fengjuan
[1
,2
]
Xu, Zhihong
[3
]
Bai, Decheng
[4
]
Zeng, Zhengzhi
[1
,2
]
机构:
[1] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China
[3] Xuchang Univ, Coll Chem & Chem Engn, Xuchang 461000, Peoples R China
[4] Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Peoples R China
关键词:
FLUORESCENT CHEMOSENSOR;
MERCURY;
CU(II);
SENSOR;
ION;
FLUOROIONOPHORE;
CHROMOIONOPHORE;
RECOGNITION;
ETHER;
PROBE;
D O I:
10.1039/c1dt10573f
中图分类号:
O61 [无机化学];
学科分类号:
070301 ;
081704 ;
摘要:
A turn-on chemosensor L1, which exhibits high selectivity and sensitivity toward Hg2+ over other common metal ions in aqueous media under a physiological pH window via a 1:1 binding mode, had been synthesized and characterized. L1 provides good fluorescent imaging of Hg2+ in living cells. Particularly, we adopted the "micro computed tomography (MCT)" technology, successfully demonstrating the method of Hg2+ sensing by L1 in cell lines, also the cell permeability of L1 and its imaging position in the cells.
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页码:6382 / 6384
页数:3
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