Weight change since age 20 and incident risk of obesity-related cancer in Japan: a pooled analysis of the Miyagi Cohort Study and the Ohsaki Cohort Study

被引:17
作者
Wakamatsu, Mano [1 ]
Sugawara, Yumi [1 ]
Zhang, Shu [1 ]
Tanji, Fumiya [1 ]
Tomata, Yasutake [1 ]
Tsuji, Ichiro [1 ]
机构
[1] Tohoku Univ, Sch Publ Hlth, Grad Sch Med, Div Epidemiol,Dept Hlth Informat & Publ Hlth, Sendai, Miyagi, Japan
关键词
weight change; obesity-related cancer; Cohort; Japan; incidence; COLORECTAL-CANCER; GAIN; METAANALYSIS; ASSOCIATION; ADULTHOOD; HEALTH; LIFE;
D O I
10.1002/ijc.31743
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
It is unclear whether weight change during adulthood affects the risk of obesity-related cancers such as those of the esophagus, colorectum, pancreas, breast, endometrium, and kidney among Japanese, where obesity is less frequent and less severe. We examined the association between weight change during adulthood and the risk of obesity-related cancer among Japanese by conducting a pooled analysis of two prospective studies of residents in Miyagi Prefecture, Japan. A total of 78,743 persons (40,422 women and 38,321 men) aged 40-79 years participated in the Miyagi Cohort Study in 1990 and in the Ohsaki Cohort Study in 1994. Weight change since age 20 was divided into four categories (weight loss; stable weight; moderate weight gain; high weight gain). Cox proportional hazards regression analysis was used to estimate the multivariate hazard ratios (HRs) and 95% confidence intervals (CIs) for obesity-related cancer incidence. During 1,057,899 person-years of follow up, 4,467 cases of obesity-related cancer (women; 1,916 cases, men; 2,551cases) were identified. In women, compared to the stable weight, weight gain was associated with an increased risk of obesity-related cancer (moderate weight gain; HRs = 1.10, 95%CIs: 0.97-1.26, high weight gain; HRs = 1.29, 95%CIs: 1.14-1.47). The results indicate that weight gain since age 20 was associated with a significantly increased risk of obesity-related cancer among Japanese women. By contrast, in men, our study found that weight change is not associated with the incidence of obesity-related cancer.
引用
收藏
页码:967 / 980
页数:14
相关论文
共 31 条
[1]   Adult weight change and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition [J].
Aleksandrova, Krasimira ;
Pischon, Tobias ;
Buijsse, Brian ;
May, Anne M. ;
Peeters, Petra H. ;
Bueno-de-Mesquita, H. Bas ;
Jenab, Mazda ;
Fedirko, Veronika ;
Dahm, Christina C. ;
Siersema, Peter D. ;
Freisling, Heinz ;
Ferrari, Pietro ;
Overvad, Kim ;
Tjonneland, Anne ;
Trichopoulou, Antonia ;
Lagiou, Pagona ;
Naska, Androniki ;
Pala, Valeria ;
Mattiello, Amalia ;
Ohlsson, Bodil ;
Jirstrom, Karin ;
Key, Timothy J. ;
Khaw, Kay-Tee ;
Riboli, Elio ;
Boeing, Heiner .
EUROPEAN JOURNAL OF CANCER, 2013, 49 (16) :3526-3536
[2]  
[Anonymous], 2007, Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective, P517
[3]  
[Anonymous], 2017, DIET NUTR PHYS ACT B
[4]   Obesity and Cancer Risk: Recent Review and Evidence [J].
Basen-Engquist, Karen ;
Chang, Maria .
CURRENT ONCOLOGY REPORTS, 2011, 13 (01) :71-76
[5]   Weight change later in life and colon and rectal cancer risk in participants in the EPIC-PANACEA study [J].
Bisschop, Charlotte N. Steins ;
van Gils, Carla H. ;
Emaus, Marleen J. ;
Bueno-de-Mesquita, H. Bas ;
Monninkhof, Evelyn M. ;
Boeing, Heiner ;
Aleksandrova, Krasmira ;
Jenab, Mazda ;
Norat, Teresa ;
Riboli, Elio ;
Boutron-Ruault, Marie-Christine ;
Fagherazzi, Guy ;
Racine, Antoine ;
Palli, Domenico ;
Krogh, Vittorio ;
Tumino, Rosario ;
Naccarati, Alessio ;
Mattiello, Amalia ;
Vicente Argueeles, Marcial ;
Jose Sanchez, Maria ;
Jose Tormo, Maria ;
Ardanaz, Eva ;
Dorronsoro, Miren ;
Bonet, Catalina ;
Khaw, Kay-Tee ;
Key, Tim ;
Trichopoulou, Antonia ;
Orfanos, Philippos ;
Naska, Androniki ;
Kaaks, Rudolph R. ;
Lukanova, Annekatrin ;
Pischon, Tobias ;
Ljuslinder, Ingrid ;
Jirstrom, Karin ;
Ohlsson, Bodil ;
Overvad, Kim ;
Berentzen, Tina Landsvig ;
Halkjaer, Jytte ;
Tjonneland, Anne ;
Weiderpass, Elisabete ;
Skeie, Guri ;
Braaten, Tonje ;
Siersema, Peter D. ;
Freisling, Heinz ;
Ferrari, Pietro ;
Peeters, Petra H. M. ;
May, Anne M. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2014, 99 (01) :139-147
[6]   Association between adult weight gain and colorectal cancer: A dose-response meta-analysis of observational studies [J].
Chen, Qi ;
Wang, Jing ;
Yang, Jinghui ;
Jin, Zhichao ;
Shi, Wentao ;
Qin, Yingyi ;
Yu, Feifei ;
He, Jia .
INTERNATIONAL JOURNAL OF CANCER, 2015, 136 (12) :2880-2889
[7]   Estrogen plus progestin and colorectal cancer in postmenopausal women [J].
Chlebowski, RT ;
Wactawski-Wende, J ;
Ritenbaugh, C ;
Hubbell, FA ;
Ascensao, J ;
Rodabough, RJ ;
Rosenberg, CA ;
Taylor, VM ;
Harris, R ;
Chen, C ;
Adams-Campbell, LL ;
White, E ;
Alving, B ;
Rossouw, J ;
Pottern, L ;
Ludlam, S ;
McGowan, J ;
Prentice, R ;
Anderson, G ;
LaCroix, A ;
Patterson, R ;
McTiernan, A ;
Cochrane, B ;
Hunt, J ;
Tinker, L ;
Kooperberg, C ;
McIntosh, M ;
Wang, CY ;
Chen, C ;
Bowen, D ;
Kristal, A ;
Stanford, J ;
Urban, N ;
Weiss, N ;
White, E ;
Shumaker, S ;
Rautaharju, P ;
Prineas, R ;
Naughton, M ;
Stein, E ;
Laskarzewski, P ;
Cummings, S ;
Nevitt, M ;
Dockrell, M ;
Harnack, L ;
Cammarata, F ;
Lindenfelser, S ;
Psaty, B ;
Heckbert, S ;
Wassertheil-Smoller, S .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (10) :991-1004
[8]   Overweight in Early Adulthood, Adult Weight Change, and Risk of Type 2 Diabetes, Cardiovascular Diseases, and Certain Cancers in Men: a Cohort Study [J].
de Mutsert, Renee ;
Sun, Qi ;
Willett, Walter C. ;
Hu, Frank B. ;
van Dam, Rob M. .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2014, 179 (11) :1353-1365
[9]   Obesity as a Major Risk Factor for Cancer [J].
De Pergola, Giovanni ;
Silvestris, Franco .
JOURNAL OF OBESITY, 2013, 2013
[10]   Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants [J].
Di Cesare, Mariachiara ;
Bentham, James ;
Stevens, Gretchen A. ;
Zhou, Bin ;
Danaei, Goodarz ;
Lu, Yuan ;
Bixby, Honor ;
Cowan, Melanie J. ;
Riley, Leanne M. ;
Hajifathalian, Kaveh ;
Fortunato, Lea ;
Taddei, Cristina ;
Bennett, James E. ;
Ikeda, Nayu ;
Khang, Young-Ho ;
Kyobutungi, Catherine ;
Laxmaiah, Avula ;
Li, Yanping ;
Lin, Hsien-Ho ;
Miranda, J. Jaime ;
Mostafa, Aya ;
Turley, Maria L. ;
Paciorek, Christopher J. ;
Gunter, Marc ;
Ezzati, Majid ;
Abdeen, Ziad A. ;
Hamid, Zargar Abdul ;
Abu-Rmeileh, Niveen M. ;
Acosta-Cazares, Benjamin ;
Adams, Robert ;
Aekplakorn, Wichai ;
Aguilar-Salinas, Carlos A. ;
Ahmadvand, Alireza ;
Ahrens, Wolfgang ;
Ali, Mohamed M. ;
Alkerwi, Ala'a ;
Alvarez-Pedrerol, Mar ;
Aly, Eman ;
Amouyel, Philippe ;
Amuzu, Antoinette ;
Andersen, Lars Bo ;
Anderssen, Sigmund A. ;
Andrade, Dolores S. ;
Anjana, Ranjit Mohan ;
Aounallah-Skhiri, Hajer ;
Ariansen, Inger ;
Aris, Tahir ;
Arlappa, Nimmathota ;
Arveiler, Dominique ;
Assah, Felix K. .
LANCET, 2016, 387 (10026) :1377-1396