Isolated amyloidosis of the gastro-intestinal tract

被引:4
|
作者
Smeets, S. [1 ]
Dedeurwaerdere, F. [2 ]
Thomaere, E. [3 ]
Houthoofd, B. [3 ]
D'Hulst, L. [4 ]
Wilmes, P. [5 ]
Offner, F. [6 ]
De Coninck, S. [7 ]
机构
[1] Univ Hosp Ghent, Training, Ghent, Belgium
[2] Sint Andries Hosp, Dept Anatomopathol, Tielt, Belgium
[3] Sint Andries Hosp, Dept Radiol, Tielt, Belgium
[4] Sint Andries Hosp, Dept Nucl Med, Tielt, Belgium
[5] Sint Andries Hosp, Dept Oncol, Tielt, Belgium
[6] Univ Hosp Ghent, Dept Hematol, Ghent, Belgium
[7] Sint Andries Hosp, Dept Gastroenterol, Tielt, Belgium
关键词
Amyloidosis; gastro-intestinal amyloid deposition; SYSTEMIC AMYLOIDOSIS; OLD-AGE; DIAGNOSIS; FIBRIL; FEATURES; THERAPY; DISEASE;
D O I
10.51821/85.1.8499
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Amyloidosis is a very rare condition, which, due to its rarity, is often missed or diagnosed in an advanced stage of the disease, causing significant morbidity and mortality. In this review we describe the existing types of amyloidosis focusing on the gastro-intestinal tract. Amyloidosis occurs when abnormal protein fibrils (amyloid) deposit in the muscularis mucosae. This can cause an array of symptoms ranging from (in order of occurrence): gastro-intestinal bleeding, heartburn, unintentional weight loss, early satiety, constipation, diarrhea, nausea, vomiting and fecal incontinence (1). Treatment is focused on the underlying condition (if any) causing the production and deposition of the abnormal fibrils, in combination of symptomatic treatment. (Acta gastroenterol. belg., 2022, 85, 80-84).
引用
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页码:80 / 84
页数:5
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