Pericarditis: a rare complication of methotrexate therapy

被引：10

作者：

Mohyuddin, Tayyab ^{[1
]}

Elyan, Mazen ^{[1
]}

Kushner, Irving ^{[1
]}

机构：

[1] Metrohlth Med Ctr, Cleveland, OH 44109 USA

来源：

CLINICAL RHEUMATOLOGY | 2007年 / 26卷 / 12期

关键词：

methotrexate; pericarditis;

D O I：

10.1007/s10067-007-0630-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serositis is a rare complication of methotrexate (MTX) administration. We report a 60-year-old man with rheumatoid arthritis who developed pericarditis after taking his weekly MTX dose, which recurred within hours after 2 subsequent weekly MTX doses. Pericarditis has not recurred after discontinuance of MTX over 3 years ago. We conclude that he had MTX-induced pericarditis, based on the close temporal relationship between MTX ingestion and manifestations of pericarditis on three distinct occasions because of the previous reports of MTX-induced pericarditis and because pericarditis has not recurred after MTX withdrawal.

引用

页码：2157 / 2158

页数：2

共 7 条

[1] LEUKOCYTE MIGRATION-INHIBITION IN METHOTREXATE-INDUCED PNEUMONITIS - EVIDENCE FOR AN IMMUNOLOGICAL CELL-MEDIATED MECHANISM [J].