Novel Gemini Cationic Surfactants Based on N, N-Dimethyl Fatty Hydrazide and 1,3-Dibromopropane: Synthesis, Evaluation of Surface and Antimicrobial Properties

A fatty hydrazide based cationic gemini surfactants, 1,3-bis (N'-acyl-N,N-dimethylhydrazinium) propane dibromide which possess hydrolyzable amido moieties in the lipophilic portions, were prepared by reacting 1,3-bromopropane with N,N-dimethyl fatty hydrazide. The surface properties were explained and discussed based on the effect of their chemical structures. The micelle-forming ability, foaming ability, and foam stability were evaluated. The prepared surfactants also showed some antimicrobial activity against gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) but they were not active against gram negative bacteria (Escherichia con, P aeruginosa), yeast (Candida albicans), and molds (Aspergillus niger).