The coaction of tonic and phasic dopamine dynamics

被引：66

作者：

Atcherley, Christopher W. ^{[1
]}

Wood, Kevin M. ^{[2
]}

Parent, Kate L. ^{[1
]}

Hashemi, Parastoo ^{[2
]}

Heien, Michael L. ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem & Biochem, Tucson, AZ 85721 USA

[2] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 12期

关键词：

CARBON-FIBER MICROELECTRODES; REAL-TIME MEASUREMENT; NUCLEUS-ACCUMBENS; EXTRACELLULAR CONCENTRATION; BRAIN MICRODIALYSIS; CYCLIC VOLTAMMETRY; RELEASE; NEUROTRANSMITTERS; DIFFUSION; RATS;

D O I：

10.1039/c4cc06165a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 +/- 9 nM) and the dopamine diffusion coefficient (1.05 +/- 0.09 x 10(-6) cm(2) s(-1)) in the mouse brain.

引用

页码：2235 / 2238

页数：4

共 43 条

[1]

Atcherley C. W., 2014, ACS CHEM NEUROSCI, DOI [10.1021/cn500020s, DOI 10.1021/CN500020S]

[2] Fast-Scan Controlled-Adsorption Voltammetry for the Quantification of Absolute Concentrations and Adsorption Dynamics [J].

Atcherley, Christopher W. ;

Laude, Nicholas D. ;

Parent, Kate L. ;

Heien, Michael L. .

LANGMUIR, 2013, 29 (48) :14885-14892

[3] Rethinking Data Collection and Signal Processing. 2. Preserving the Temporal Fidelity of Electrochemical Measurements [J].

Atcherley, Christopher W. ;

Vreeland, Richard F. ;

Monroe, Eric B. ;

Sanchez-Gomez, Esther ;

Heien, Michael L. .

ANALYTICAL CHEMISTRY, 2013, 85 (16) :7654-7658

[4] PARKINSONIAN-LIKE LOCOMOTOR IMPAIRMENT IN MICE LACKING DOPAMINE D2 RECEPTORS [J].

BAIK, JH ;

PICETTI, R ;

SAIARDI, A ;

THIRIET, G ;

DIERICH, A ;

DEPAULIS, A ;

LEMEUR, M ;

BORRELLI, E .

NATURE, 1995, 377 (6548) :424-428

[5] Voltammetric study of the control of striatal dopamine release by glutamate [J].

Borland, LM ;

Michael, AC .

JOURNAL OF NEUROCHEMISTRY, 2004, 91 (01) :220-229

[6] Microelectrodes for the measurement of catecholamines in biological systems [J].

Cahill, PS ;

Walker, QD ;

Finnegan, JM ;

Mickelson, GE ;

Travis, ER ;

Wightman, RM .

ANALYTICAL CHEMISTRY, 1996, 68 (18) :3180-3186

[7] Quantitative no-net-flux microdialysis permits detection of increases and decreases in dopamine uptake in mouse nucleus accumbens [J].

Chefer, Vladimir I. ;

Zapata, Agustin ;

Shippenberg, Toni S. ;

Bungay, Peter M. .

JOURNAL OF NEUROSCIENCE METHODS, 2006, 155 (02) :187-193

[8] DAncing past the DAT at a DA synapse [J].

Cragg, SJ ;

Rice, ME .

TRENDS IN NEUROSCIENCES, 2004, 27 (05) :270-277

[9] Influence of Phasic and Tonic Dopamine Release on Receptor Activation [J].

Dreyer, Jakob K. ;

Herrik, Kjartan F. ;

Berg, Rune W. ;

Hounsgaard, Jorn D. .

JOURNAL OF NEUROSCIENCE, 2010, 30 (42) :14273-14283

[10] Mathematical model of dopamine autoreceptors and uptake inhibitors and their influence on tonic and phasic dopamine signaling [J].

Dreyer, Jakob Kisbye ;

Hounsgaard, Jorn .

JOURNAL OF NEUROPHYSIOLOGY, 2013, 109 (01) :171-182

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