Self-assembled benzoselenadiazole-capped tripeptide hydrogels with inherent in vitro anti-cancer and anti-inflammatory activity

被引:12
作者
Ghosh, Tapas [1 ]
Wang, Shu [2 ]
Kashyap, Dharmendra [3 ]
Jadhav, Rohit G. [1 ]
Rit, Tanmay [1 ]
Jha, Hem Chandra [3 ]
Cousins, Brian G. [2 ]
Das, Apurba K. [1 ]
机构
[1] Indian Inst Technol Indore, Dept Chem, Indore 453552, Madhya Pradesh, India
[2] Loughborough Univ, Dept Chem, Loughborough LE11 3TU, Leics, England
[3] Indian Inst Technol Indore, Dept Biosci & Biomed Engn, Indore 453552, Madhya Pradesh, India
关键词
RATIONAL DESIGN; DRUG-DELIVERY; AMINO-ACIDS; PEPTIDE; APOPTOSIS; CELLS; CYTOKINES;
D O I
10.1039/d2cc01160c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Self-assembled benzoselenadiazole (BSe)-capped tripeptide based nanofibrillar hydrogels have been developed with inherent anticancer and anti-inflammatory activity.
引用
收藏
页码:7534 / 7537
页数:4
相关论文
共 34 条
[1]   The design, synthesis and evaluation of selenium-containing 4-anilinoquinazoline hybrids as anticancer agents and a study of their mechanism [J].
An, Baijiao ;
Zhang, Shun ;
Hu, Jinhui ;
Pan, Tingting ;
Huang, Ling ;
Tang, Johnny Cheuk-on ;
Li, Xingshu ;
Chan, Albert S. C. .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 16 (25) :4701-4714
[2]   Development and Therapeutic Potential of Selenazo Compounds [J].
Carolina Ruberte, Ana ;
Sanmartin, Carmen ;
Aydillo, Carlos ;
Sharma, Arun K. ;
Plano, Daniel .
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (04) :1473-1489
[3]   Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative [J].
Chen, Tianfeng ;
Zheng, Wenjie ;
Wong, Yum-Shing ;
Yang, Fang .
BIOMEDICINE & PHARMACOTHERAPY, 2008, 62 (02) :77-84
[4]   Caspase- and p53-dependent apoptosis in breast carcinoma cells induced by a synthetic selenadiazole derivative [J].
Chen, Tianfeng ;
Wong, Yum-Shing ;
Zheng, Wenjie ;
Liu, Jie .
CHEMICO-BIOLOGICAL INTERACTIONS, 2009, 180 (01) :54-60
[5]   Tunable Pentapeptide Self-Assembled β-Sheet Hydrogels [J].
Clarke, David E. ;
Parmenter, Christopher D. J. ;
Scherman, Oren A. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (26) :7709-7713
[6]   Low molecular weight self-assembling peptide-based materials for cell culture, antimicrobial, anti-inflammatory, wound healing, anticancer, drug delivery, bioimaging and 3D bioprinting applications [J].
Das, Apurba K. ;
Gavel, Pramod K. .
SOFT MATTER, 2020, 16 (44) :10065-10095
[7]   Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials [J].
Du, Xuewen ;
Zhou, Jie ;
Shi, Junfeng ;
Xu, Bing .
CHEMICAL REVIEWS, 2015, 115 (24) :13165-13307
[8]   Apoptosis: A review of programmed cell death [J].
Elmore, Susan .
TOXICOLOGIC PATHOLOGY, 2007, 35 (04) :495-516
[9]   Investigations of Anti-Inflammatory Activity of a Peptide-Based Hydrogel Using Rat Air Pouch Model [J].
Gavel, Pramod K. ;
Parmar, Hamendra S. ;
Tripathi, Versha ;
Kumar, Narendra ;
Biswas, Ankan ;
Das, Apurba K. .
ACS APPLIED MATERIALS & INTERFACES, 2019, 11 (03) :2849-2859
[10]   Heterochiral Assembly of Amphiphilic Peptides Inside the Mitochondria for Supramolecular Cancer Therapeutics [J].
Jeena, M. T. ;
Jeong, Keunsoo ;
Go, Eun Min ;
Cho, Yuri ;
Lee, Seokyung ;
Jin, Seongeon ;
Hwang, Suk-Won ;
Jang, Joo Hee ;
Kang, Chi Soo ;
Bang, Woo-Young ;
Lee, Eunji ;
Kwak, Sang Kyu ;
Kim, Sehoon ;
Ryu, Ja-Hyoung .
ACS NANO, 2019, 13 (10) :11022-11033