Biotechnological Intervention and Secondary Metabolite Production in Centella asiatica L.

被引:4
作者
Ganie, Irfan Bashir [1 ]
Ahmad, Zishan [2 ,3 ]
Shahzad, Anwar [1 ]
Zaushintsena, Alexandra [4 ,5 ]
Neverova, Olga [5 ]
Ivanova, Svetlana [6 ,7 ]
Wasi, Adla [1 ]
Tahseen, Sabaha [1 ]
机构
[1] Aligarh Muslim Univ, Dept Bot, Plant Biotechnol Lab, Aligarh 202002, Uttar Pradesh, India
[2] Nanjing Forestry Univ, Coinnovat Ctr Sustainable Forestry Southern China, Nanjing 210037, Peoples R China
[3] Nanjing Forestry Univ, Bamboo Res Inst, Nanjing 210037, Peoples R China
[4] Kemerovo State Univ, Res Inst Biotechnol, Krasnaya St 6, Kemerovo 650043, Russia
[5] Kemerovo State Univ, Dept Ecol & Nat Management, Krasnaya St 6, Kemerovo 650043, Russia
[6] Kemerovo State Univ, Nat Nutraceut Biotesting Lab, Krasnaya St 6, Kemerovo 650043, Russia
[7] Kemerovo State Univ, Dept Gen Math & Informat, Krasnaya St, Kemerovo 650043, Russia
来源
PLANTS-BASEL | 2022年 / 11卷 / 21期
关键词
Centella asiatica; elicitation; hairy root culture; micropropagation; synthetic seeds; triterpenoids; ADVENTITIOUS ROOT CULTURES; IN-VITRO MULTIPLICATION; SOMATIC EMBRYOGENESIS; PLANT-REGENERATION; CELL-CULTURES; INDUCED PARKINSONISM; MEDICINAL HERB; URBAN; ACID; MICROPROPAGATION;
D O I
10.3390/plants11212928
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Centella asiatica L., commonly known as Gotu kola, Indian penny-wort, and Asiatic pennyworts, is an herbaceous perennial plant that belongs to the family Apiaceae and has long been used in the traditional medicine system. The plant is known to produce a wide range of active metabolites such as triterpenoids including asiatic acid, asiaticoside, brahmoside, and madecassic acid along with other constituents including centellose, centelloside, and madecassoside, etc., which show immense pharmacological activity. Due to its beneficial role in neuroprotection activity, the plant has been considered as a brain tonic. However, limited cultivation, poor seed viability with low germination rate, and overexploitation for decades have led to severe depletion and threatened its wild stocks. The present review aimed to provide up-to-date information on biotechnological tools applied to this endangered medicinal plant for its in vitro propagation, direct or indirect regeneration, synthetic seed production, strategies for secondary metabolite productions including different elicitors. In addition, a proposed mechanism for the biosynthesis of triterpenoids is also discussed.
引用
收藏
页数:24
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