Homogeneous asymmetric transfer hydrogenation of ketones using a ruthenium catalyst anchored on chitosan: natural chirality at work

被引：30

作者：

Babin, Mathieu ^{[1
,2
,3
]}

Clement, Roxanne ^{[4
]}

Gagnon, Jonathan ^{[1
]}

Fontaine, Frederic-Georges ^{[2
,3
]}

机构：

[1] Univ Quebec, Dept Biol Chim & Geog, Rimouski, PQ G5L 3A1, Canada

[2] Univ Laval, Dept Chim, Quebec City, PQ G1V 0A6, Canada

[3] Univ Laval, Ctr Rech Proprietes Interfaces & Catalyse CERPIC, Quebec City, PQ G1V 0A6, Canada

[4] Univ Ottawa, Ctr Catalysis Res & Innovat, Ottawa, ON K1N 6N5, Canada

来源：

NEW JOURNAL OF CHEMISTRY | 2012年 / 36卷 / 08期

基金：

加拿大自然科学与工程研究理事会;

关键词：

COMPLEXES; LIGANDS; BEHAVIOR;

D O I：

10.1039/c2nj40175d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A pivaloyl functionalized chitosan biopolymer was used as a polyligand for the [Ru(p-cymene)Cl-2] moiety. The functionalized biopolymer containing a metal to saccharide ratio of 0.33 was used as a catalyst for the asymmetric transfer hydrogenation of ketones. The reactions gave yields up to 80% and enantiomeric excesses up to 72%, with the intrinsic chirality of chitosan being the only source of enantioselection.

引用

页码：1548 / 1551

页数：4

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