Synthesis, crystal structure, characterization, and microbial evaluation of (E)-N-(4-isopropylbenzylidene)thiophene-2-carbohydrazide

被引:2
作者
Rajavel, A. [1 ]
Jeyakumar, T. [2 ]
Sundararajan, M. L. [2 ]
Srinivasan, T. [3 ]
Velmurugan, D. [4 ]
机构
[1] Annamalai Univ, Dept Chem, Annamalainagar, Tamil Nadu, India
[2] Annamalai Univ, Fac Engn & Technol, Chem Sect, Annamalainagar, Tamil Nadu, India
[3] Vel Tech Univ, Dept Phys, Chennai, Tamil Nadu, India
[4] Univ Madras, Ctr Adv Study Crystallog & Biophys, Chennai, Tamil Nadu, India
关键词
Cuminaldehyde:2-thiophene-carboxylic acid hydrazide; mass spectra Anti oxidant properties; MICROWAVE-ASSISTED SYNTHESIS; ANTIBACTERIAL ACTIVITY; DERIVATIVES; THIOPHENE; ACID;
D O I
10.1080/15421406.2016.1170285
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(E)-N-(4-isopropylbenzylidene)thiophene-2-carbohydrazide (L) was prepared and characterized using elemental analysis, UV-visible, IR, H-1 and C-13 NMR, mass spectra. The crystal structure of L was determined by single-crystal X-ray diffraction method. The compound L crystallizes in monoclinic space group P2(1)/n with a = 16.676(5) angstrom, b = 5.475(5) angstrom, c = 17.022(5) angstrom, and Z = 4. Antimicrobial and antifungal activity was assayed against four bacterial and four fungal microorganisms. The antioxidant behavior of L was also investigated. [GRAPHICS] .
引用
收藏
页码:176 / 186
页数:11
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