Determination of butyl- and phenyltin compounds in biological material by gas chromatography flame photometric detection after ethylation with sodium tetraethylborate

被引：37

作者：

CarlierPinasseau, C

Astruc, A

Lespes, G

Astruc, M

机构：

来源：

JOURNAL OF CHROMATOGRAPHY A | 1996年 / 750卷 / 1-2期

关键词：

ethylation; derivatization; GC; extraction methods; butyltin compounds; phenyltin compounds; organotin compounds; sodium tetraethylborate;

D O I：

10.1016/0021-9673(96)00542-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A reliable and rapid speciation method for the simultaneous determination of butyl- and phenyltin species in biological samples has been developed. Three extraction procedures are compared: enzymatic hydrolysis and solubilization by ethanoic and hydrochloric acids. Derivatization is performed by the one-step ethylation/extraction procedure using the sodium tetraethylborate reagent directly in the aqueous phase in the presence of an isooctane layer. Analysis is performed using capillary gas chromatography coupled to flame photometric detection. The detection limits are in the range of a few ng(Sn)/g. Analysis of the environmental samples and the certified reference material demonstrates the accuracy of the analytical method.

引用

页码：317 / 325

页数：9

共 33 条

[21] DETERMINATION OF TRIBUTYLTIN AND TRIPHENYLTIN COMPOUNDS IN HAIR AND FISH USING A HYDROLYSIS TECHNIQUE AND GAS-CHROMATOGRAPHY WITH FLAME PHOTOMETRIC DETECTION [J].