First Serological Evidence of West Nile Virus Activity in Horses in Serbia

被引:50
作者
Lupulovic, Diana [2 ]
Martin-Acebes, Miguel A. [1 ]
Lazic, Sava [2 ]
Alonso-Padilla, Julio [1 ]
Blazquez, Ana-Belen [1 ]
Escribano-Romero, Estela [1 ]
Petrovic, Tamas [2 ]
Saiz, Juan-Carlos [1 ]
机构
[1] Inst Nacl Invest Agr, Dept Biotecnol, Madrid 28040, Spain
[2] Sci Vet Inst Novi Sad, Novi Sad, Serbia
关键词
Horses; Serbia; Usutu virus; Vector-borne; West Nile virus; USUTU-VIRUS; ENCEPHALITIS; INFECTION;
D O I
10.1089/vbz.2010.0249
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
West Nile virus (WNV), the most widely distributed flavivirus worldwide, has lately reemerged in Europe, causing worrisome outbreaks in humans and horses. Serological analysis by enzyme-linked immunoassay and plaque reduction neutralization test showed for the first time in Serbia that 12% of 349 horses presented specific neutralizing WNV antibodies, which in one case also cross-neutralized Usutu virus (USUV). This is the first time that anti-USUV high neutralizing antibody titers are reported in horses. All these data indicate that WNV and USUV are circulating in the region and advise on the convenience of implementing surveillance programs.
引用
收藏
页码:1303 / 1305
页数:3
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