Metabolites from an Antarctic sponge-associated bacterium, Pseudomonas aeruginosa

被引：229

作者：

Jayatilake, GS

Thornton, MP

Leonard, AC

Grimwade, JE

Baker, BJ

机构：

[1] FLORIDA INST TECHNOL,DEPT CHEM,MELBOURNE,FL 32901

[2] FLORIDA INST TECHNOL,DEPT BIOL SCI,MELBOURNE,FL 32901

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 03期

关键词：

D O I：

10.1021/np960095b

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In an ongoing survey of the bioactive potential of microorganisms associated with marine invertebrates, the culture media of a sponge-associated bacterial strain of Pseudomonas aeruginosa was found to contain metabolites which inhibit the growth pf several Gram-positive microorganisms. A series of diketopiperazines (1-6) including a new natural product (6) and two known phenazine alkaloid antibiotics (7 and 8) were isolated from the culture broth of this bacterium.

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页码：293 / 296

页数：4

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