On the problem of local tissue hyperthermia control: multiscale modelling of pulsed laser radiation action on a medium with embedded nanoparticles

被引:16
作者
Avetisyan, Yu. A. [1 ]
Yakunin, A. N. [1 ]
Tuchin, V. V. [2 ,3 ]
机构
[1] Russian Acad Sci, Inst Problems Precis Mech & Control, Saratov 410028, Russia
[2] Russian Acad Sci, Inst Precis Mech & Control, Saratov 410028, Russia
[3] NG Chernyshevsky Saratov State Univ, Saratov 410012, Russia
关键词
time-dependent temperature field modelling; laser hyperthermia; composite nanoparticles; MULTILAYER BIOLOGICAL TISSUE; THERMAL-PROCESSES; SIMULATION;
D O I
10.1070/QE2010v040n12ABEH014502
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Methods for solving analytically and numerically the problem of multiscale modelling of the laser hyperthermia processes in a medium with nanoparticles are developed with regard to composite spherical nanoparticles (nanoshells). The features of the laser radiation field localisation on nanoscale inhomogeneities are investigated. Issues related to the control of the tissue hyperthermia processes by choosing the parameters of spatiotemporal localisation of the laser beam and of the absorbing nanoparticles are discussed.
引用
收藏
页码:1081 / 1088
页数:8
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