Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles.: Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds

被引：48

作者：

Asaumi, T ^{[1
]}

Chatani, N ^{[1
]}

Matsuo, T ^{[1
]}

Kakiuchi, F ^{[1
]}

Murai, S ^{[1
]}

机构：

[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 19期

关键词：

D O I：

10.1021/jo0343127

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 1-arylpyrazoles with CO and ethylene in the presence of Ru-3(CO)(12) resulted in regioselective carbonylation at the ortho C-H bonds. While it is found that the pyrazole ring also functions as the directing group for C-H bond cleavage, the efficiency of the reaction depends on the position of the pyrazole ring.

引用

页码：7538 / 7540

页数：3

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