Continuous Antibiotic Prophylaxis in Pediatric Urology

被引：10

作者：

Storm, Douglas W. ^{[1
]}

Braga, Luis H. ^{[2
]}

Cooper, Christopher S. ^{[1
]}

机构：

[1] Univ Iowa, Dept Urol, Carver Coll Med, 200 Hawkins Dr,3RCP, Iowa City, IA 52242 USA

[2] McMaster Univ, McMaster Childrens Hosp, Dept Surg, Div Urol, 1200 Main St West, Hamilton, ON L8N 3Z5, Canada

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2018年 / 45卷 / 04期

关键词：

Antibiotic prophylaxis; Vesicoureteral reflux; Prenatal hydronephrosis; Antibiotic resistance; Microbiota; Megaureter; Side effects; URINARY-TRACT-INFECTION; PRIMARY VESICOURETERAL REFLUX; TERM FOLLOW-UP; GUT MICROBIOTA; RISK-FACTORS; ANTENATAL HYDRONEPHROSIS; PRENATAL HYDRONEPHROSIS; ESCHERICHIA-COLI; CRANBERRY JUICE; EARLY-LIFE;

D O I：

10.1016/j.ucl.2018.06.001

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Continuous antibiotic prophylaxis (CAP) for urinary tract infection prevention in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis is reviewed. A more selective use of CAP is advocated based on a review of known individual risk factors in each of these conditions that subsequently helps identify the children most likely to benefit from CAP. Both short-term and potential long-term side effects of CAP are reviewed, including the impact of prophylactic antibiotics on bacterial resistance and the microbiome. Alternatives to continuous antibiotic prophylaxis including Vaccinium macrocarpon (Cranberry), probiotics, and vaccines are reviewed.

引用

页码：525 / +

页数：15

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