Continuous Antibiotic Prophylaxis in Pediatric Urology

被引：10
作者：
Storm, Douglas W. [1 ]
Braga, Luis H. [2 ]
Cooper, Christopher S. [1 ]
机构：
[1] Univ Iowa, Dept Urol, Carver Coll Med, 200 Hawkins Dr,3RCP, Iowa City, IA 52242 USA
[2] McMaster Univ, McMaster Childrens Hosp, Dept Surg, Div Urol, 1200 Main St West, Hamilton, ON L8N 3Z5, Canada
来源：
UROLOGIC CLINICS OF NORTH AMERICA | 2018年 / 45卷 / 04期
关键词：
Antibiotic prophylaxis; Vesicoureteral reflux; Prenatal hydronephrosis; Antibiotic resistance; Microbiota; Megaureter; Side effects; URINARY-TRACT-INFECTION; PRIMARY VESICOURETERAL REFLUX; TERM FOLLOW-UP; GUT MICROBIOTA; RISK-FACTORS; ANTENATAL HYDRONEPHROSIS; PRENATAL HYDRONEPHROSIS; ESCHERICHIA-COLI; CRANBERRY JUICE; EARLY-LIFE;
D O I：
10.1016/j.ucl.2018.06.001
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Continuous antibiotic prophylaxis (CAP) for urinary tract infection prevention in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis is reviewed. A more selective use of CAP is advocated based on a review of known individual risk factors in each of these conditions that subsequently helps identify the children most likely to benefit from CAP. Both short-term and potential long-term side effects of CAP are reviewed, including the impact of prophylactic antibiotics on bacterial resistance and the microbiome. Alternatives to continuous antibiotic prophylaxis including Vaccinium macrocarpon (Cranberry), probiotics, and vaccines are reviewed.
引用
收藏
页码：525 / +
页数：15
相关论文
共 135 条
[71]   Risk Factors for Catheter Associated Urinary Tract Infections in a Pediatric Institution [J].
Lee, Nora G. ;
Marchalik, Daniel ;
Lipsky, Andrew ;
Rushton, H. Gil ;
Pohl, Hans G. ;
Song, Xiaoyan .
JOURNAL OF UROLOGY, 2016, 195 (04) :1306-1311
[72]   NATURAL-HISTORY OF REFLUX AND LONG-TERM EFFECTS OF REFLUX ON KIDNEY [J].
LENAGHAN, D ;
WHITAKER, JG ;
JENSEN, F ;
STEPHENS, FD .
JOURNAL OF UROLOGY, 1976, 115 (06) :728-730
[73]   Outcome of Antibiotic Prophylaxis Discontinuation in Patients With Persistent Vesicoureteral Reflux Initially Presenting With Febrile Urinary Tract Infection: Time to Event Analysis [J].
Leslie, Bruno ;
Moore, Katherine ;
Salle, Joao L. Pippi ;
Khoury, Antoine E. ;
Cook, Anthony ;
Braga, Luis H. P. ;
Baegli, Darius J. ;
Lorenzo, Armando J. .
JOURNAL OF UROLOGY, 2010, 184 (03) :1093-1098
[74]   Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation of childhood [J].
LoeningBaucke, V .
PEDIATRICS, 1997, 100 (02) :228-232
[75]   THE ACTIVITY OF SYNTHETIC FOLIC ACID IN PURIFIED RATIONS FOR THE CHICK [J].
LUCKEY, TD ;
MOORE, PR ;
ELVEHJEM, CA ;
HART, EB .
SCIENCE, 1946, 103 (2684) :682-684
[76]   RECURRENT URINARY-TRACT INFECTIONS IN CHILDREN [J].
MCCRACKEN, GH .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1984, 3 (03) :S28-S30
[77]   Bladder volume at onset of reflux on initial cystogram predicts spontaneous resolution [J].
McMillan, Zeb M. ;
Austin, J. Christopher ;
Knudson, Matthew J. ;
Hawtrey, Charles E. ;
Cooper, Christopher S. .
JOURNAL OF UROLOGY, 2006, 176 (04) :1838-1841
[78]   Variation Among Pediatric Urologists and Across 2 Continents in Antibiotic Prophylaxis and Evaluation for Prenatally Detected Hydronephrosis: A Survey of American and European Pediatric Urologists [J].
Merguerian, Paul A. ;
Herz, Daniel ;
McQuiston, Leslie ;
Van Bibber, Michael .
JOURNAL OF UROLOGY, 2010, 184 (04) :1710-1715
[79]   Abnormal dimercapto-succinic acid scans predict an increased risk of breakthrough infection in children with vesicoureteral reflux [J].
Mingin, GC ;
Nguyen, HT ;
Baskin, LS .
JOURNAL OF UROLOGY, 2004, 172 (03) :1075-1077
[80]   Prophylaxis After First Febrile Urinary Tract Infection in Children? A Multicenter, Randomized, Controlled, Noninferiority Trial [J].
Montini, Giovanni ;
Rigon, Luca ;
Zucchetta, Pietro ;
Fregonese, Federica ;
Toffolo, Antonella ;
Gobber, Daniela ;
Cecchin, Diego ;
Pavanello, Luigi ;
Molinari, Pier Paolo ;
Maschio, Francesca ;
Zanchetta, Sergio ;
Cassar, Walburga ;
Casadio, Luca ;
Crivellaro, Carlo ;
Fortunati, Paolo ;
Corsini, Andrea ;
Calderan, Alessandro ;
Comacchio, Stefania ;
Tommasi, Lisanna ;
Hewitt, Ian K. ;
Da Dalt, Liviana ;
Zacchello, Graziella ;
Dall'Amico, Roberto .
PEDIATRICS, 2008, 122 (05) :1064-1071
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