Secretoneurin, a novel neuropeptide, in the human dental pulp

被引：12
作者：
Pertl, C
Kaufmann, W
Amann, R
Heinemann, A
Ebeleseder, K
Polansky, R
Saria, A
Kim, S
机构：
[1] Graz Univ, Sch Dent, Dept Oral Surg & Oral Radiol, A-8036 Graz, Austria
[2] Univ Innsbruck, Dept Psychiat, Neurochem Unit, A-6020 Innsbruck, Austria
[3] Graz Univ, Dept Pharmacol, Graz, Austria
[4] Graz Univ, Sch Dent, Dept Conservat Dent, A-8036 Graz, Austria
[5] Graz Univ, Sch Dent, Dept Prosthet Dent, A-8036 Graz, Austria
[6] Univ Penn, Sch Dent Med, Dept Endodont, Philadelphia, PA 19104 USA
来源：
ARCHIVES OF ORAL BIOLOGY | 1998年 / 43卷 / 05期
关键词：
secretoneurin; neuropeptides; calcitonin gene-related peptide; dental pulp;
D O I：
10.1016/S0003-9969(98)00016-8
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Secretoneurin is a neuropeptide that is stored in and released from primary afferent neurones. By radioimmunoassay and immunohistochemistry, secretoneurin was here demonstrated in the human dental pulp and localized in varicose nerve fibres that were frequently associated with blood! vessels. No significant correlation was found between the levels of immunoreactive secretoneurin and immunoreactive calcitonin-gene related peptide. The results suggest that primary afferent neurones of the human dental pulp contain secretoneurin, which may influence local inflammatory responses if it is released together with other neuropeptides. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：361 / 365
页数：5
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