HPLC Separation of Acetaminophen and its Impurities Using A Mixed-mode Reversed-Phase/Cation Exchange Stationary Phase

被引:44
|
作者
Calinescu, Octavian [1 ]
Badea, Irinel A. [1 ]
Vladescu, Luminita [1 ]
Meltzer, Viorica [2 ]
Pincu, Elena [2 ]
机构
[1] Univ Bucharest, Fac Chem, Dept Analyt Chem, Bucharest, Romania
[2] Univ Bucharest, Fac Chem, Dept Phys Chem, Bucharest, Romania
关键词
P-AMINOPHENOL; LIQUID-CHROMATOGRAPHY; SPECTROPHOTOMETRIC DETERMINATION; CAPILLARY ELECTROCHROMATOGRAPHY; PARACETAMOL; 4-AMINOPHENOL; DEGRADATION; RETENTION; TEMPERATURE; ARRAY;
D O I
10.1093/chromsci/bmr043
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:335 / 342
页数:8
相关论文
共 50 条
  • [41] A new reversed-phase/strong anion-exchange mixed-mode stationary phase based on polar-copolymerized approach and its application in the enrichment of aristolochic acids
    Wei, Jie
    Guo, Zhimou
    Zhang, Pinjie
    Zhang, Feifang
    Yang, Bingcheng
    Liang, Xinmiao
    JOURNAL OF CHROMATOGRAPHY A, 2012, 1246 : 129 - 136
  • [42] Preparation and Evaluation of Poly-l-Lysine Stationary Phase for Hydrophilic Interaction/Reversed-Phase Mixed-Mode Chromatography
    Yuanyuan Li
    Zhigang Xu
    Yaoyao Feng
    Xiaoyan Liu
    Tong Chen
    Haixia Zhang
    Chromatographia, 2011, 74 : 523 - 530
  • [43] Preparation and Evaluation of Poly-L-Lysine Stationary Phase for Hydrophilic Interaction/Reversed-Phase Mixed-Mode Chromatography
    Li, Yuanyuan
    Xu, Zhigang
    Feng, Yaoyao
    Liu, Xiaoyan
    Chen, Tong
    Zhang, Haixia
    CHROMATOGRAPHIA, 2011, 74 (7-8) : 523 - 530
  • [44] Preparation, evaluation, and application of a novel reversed-phase/zwitterionic/hydrophilic interaction liquid chromatographic mixed-mode stationary phase
    Wang, Qing
    Xu, Li
    Xue, Ying-wen
    JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2016, 39 (13) : 598 - 606
  • [45] SEPARATION OF DIHYDROGENPOLYSULFIDES (POLYSULPHANES) USING REVERSED-PHASE HPLC
    MOCKEL, HJ
    FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1984, 318 (02): : 116 - 120
  • [46] Characterization and comparison of mixed-mode and reversed-phase columns; interaction abilities and applicability for peptide separation
    Kadlecova, Zuzana
    Kozlik, Petr
    Tesarova, Eva
    Gilar, Martin
    Kalikova, Kveta
    JOURNAL OF CHROMATOGRAPHY A, 2021, 1648
  • [47] Retention prediction of highly polar ionizable solutes under gradient conditions on a mixed-mode reversed-phase and weak anion-exchange stationary phase
    Balkatzopoulou, P.
    Fasoula, S.
    Gika, H.
    Nikitas, P.
    Pappa-Louisi, A.
    JOURNAL OF CHROMATOGRAPHY A, 2015, 1396 : 72 - 76
  • [48] New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica
    Li, Yun
    Yang, Jiajia
    Jin, Jing
    Sun, Xiaoli
    Wang, Longxing
    Chen, Jiping
    JOURNAL OF CHROMATOGRAPHY A, 2014, 1337 : 133 - 139
  • [49] Preparation and evaluation of a reversed-phase/hydrophilic interaction/ion-exchange mixed-mode chromatographic stationary phase functionalized with dopamine-based dendrimers
    Zhou, Di
    Zeng, Jing
    Fu, Qifeng
    Gao, Die
    Zhang, Kailian
    Ren, Xiujun
    Zhou, Kai
    Xia, Zhining
    Wang, Lujun
    JOURNAL OF CHROMATOGRAPHY A, 2018, 1571 : 165 - 175
  • [50] Determination of S-propargyl-cysteine in rat plasma by mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method and its application to pharmacokinetic studies
    Zheng, Yuanting
    Liu, Hongrui
    Ma, Guo
    Yang, Ping
    Zhang, Lin
    Gu, Yi
    Zhu, Qing
    Shao, Tengfei
    Zhang, Peng
    Zhu, Yizhun
    Cai, Weimin
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2011, 54 (05) : 1187 - 1191